Alkaloid Synthesis (Topics in Current Chemistry) by Hans-Joachim Knölker

By Hans-Joachim Knölker

Lycopodium Alkaloids: Isolation and uneven Synthesis, through Mariko Kitajima and Hiromitsu Takayama.- Synthesis of Morphine Alkaloids and Derivatives, via Uwe Rinner and Tomas Hudlicky.- Indole Prenylation in Alkaloid Synthesis, by means of Thomas Lindel, Nils Marsch and Santosh Kumar Adla.- Marine Pyrroloiminoquinone Alkaloids, by means of Yasuyuki Kita and Hiromichi Fujioka.- man made reports on Amaryllidaceae and different Terrestrially Derived Alkaloids, by way of Martin G. Banwell, Nadia Yuqian Gao, Brett D. Schwartz and Lorenzo V. White.- Synthesis of Pyrrole and Carbazole Alkaloids, by means of Ingmar Bauer and Hans-Joachim Knölker.-

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8 Fukuyama (2010) . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 55 4 Medicinally Important Derivatives of Morphine . . . . . . . . . . . . . . . . . . . . . . 59 5 Conclusion and Outlook . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 61 References . . . . . . . . . . . . . . . . . . . . . . . . . . . .

Kobayashi J, Morita H (2005) The Lycopodium alkaloids. In: Cordell GA (ed) The alkaloids, vol 61. Elsevier, Amsterdam, pp 1–57 11. Hirasawa Y, Kobayashi J, Morita H (2009) The Lycopodium alkaloids. Heterocycles 77:679–729 12. Katakawa K, Kogure N, Kitajima M, Takayama H (2009) A new Lycopodium alkaloid, lycoposerramine-R, with a novel skeleton and three new fawcettimine-related alkaloids from Lycopodium serratum. Helv Chim Acta 92:445–452 and references cited therein 13. Liu JS, Zhu YL, Yu CM, Zhou YZ, Han YY, Wu FW, Qi BF (1986) The structures of huperzines A and B, two new alkaloids exhibiting marked anticholinesterase activity.

Nishikawa Y, Kitajima M, Takayama H (2008) First asymmetric total syntheses of cernuanetype Lycopodium alkaloids, cernuine, and cermizine D. Org Lett 10:1987–1990 55. Ramharter J, Weinstabl H, Mulzer J (2010) Synthesis of the Lycopodium alkaloid (+)-lycoflexine. J Am Chem Soc 132:14338–14339 56. De Lorbe JE, Lotz MD, Martin SF (2010) Concise total synthesis of (Æ)-lycopladine A. Org Lett 12:1576–1579 57. Yang Y-R, Lai Z-W, Shen L, Huang J-Z, Wu X-D, Yin J-L, Wei K (2010) Total synthesis of (–)-8-deoxyserratinine via an efficient Helquist annulation and double N-alkylation reaction.

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