Am I My Genes?: Confronting Fate and Family Secrets in the by Robert Klitzman

By Robert Klitzman

Within the fifty years for the reason that DNA used to be came upon, we've seen remarkable advances. for instance, genetic checking out has speedily more suitable the prognosis and therapy of ailments comparable to Huntington's, cystic fibrosis, breast melanoma, and Alzheimer's. yet with this new wisdom comes tricky judgements for numerous humans, who combat with worry approximately no matter if to get validated, and if this is the case, what to do with the consequences. Am I My Genes? exhibits how actual participants have faced those matters of their day-by-day lives.

Robert L. Klitzman interviewed sixty four those that confronted Huntington's ailment, breast and ovarian melanoma, or Alpha-1 antitrypsin deficiency. The booklet describes--often within the person's personal words--how each one has wrestled with the substantial implications that genetics has for his or her lives and their households. Klitzman exhibits how those women and men fight to make feel in their main issue and its explanations. They confront a chain of quandaries--whether to be verified; even if to reveal their genetic dangers to oldsters, siblings, spouses, offspring, pals, medical professionals, insurers, employers, and faculties; how you can view and comprehend themselves and their genetics; what remedies, if any, to pursue; even if to have childrens, undertake, monitor embryos, or abort; and no matter if to take part in genetic groups. within the face of those uncertainties, they've got attempted to appreciate those checks and percentages, stay away from fatalism, anxiousness, melancholy, and discrimination, and locate wish, that means, and a feeling of wholeness. pressured to wander via a desert of transferring sands, they chart paths that many others may possibly finally stick to.

Klitzman captures right here the voices of pioneers, a few of the first to come across the non-public dilemmas brought via glossy genetics. Am I My Genes? is a useful account in their event, person who becomes all of the extra universal within the coming years.

"An notable exploration...probing the numerous roles and implications of genetics in our lives today.... full of staggering insights, this riveting e-book is key studying for us all." -- Paula Zahn

"Klitzman lucidly discusses the ethical and mental complexities that are available the wake of genetic testing.... an immense publication for a person who has the genes for pathology, that is we all, and that i suggest it highly." -- Kay Redfield Jamison, writer of An Unquiet brain

"An illuminating voyage during the clinical, familial and existential quandaries confronted by means of these people at genetic risk." -- Thomas H. Murray, President and CEO, The Hastings heart Show

Show description

Read or Download Am I My Genes?: Confronting Fate and Family Secrets in the Age of Genetic Testing PDF

Best genetics books

Natural Computing: DNA, Quantum Bits, and the Future of Smart Machines

Reports from the innovative, the place physics and biology are altering the basic assumptions of computing.
Computers outfitted from DNA, micro organism, or foam. Robots that repair themselves on Mars. Bridges that file once they are getting older. this can be the unusual and interesting international of traditional Computing. computing device scientist and medical American’s “Puzzling Adventures” columnist Dennis Shasha right here groups up with journalist Cathy Lazere to discover the outer reaches of computing. Drawing on interviews with fifteen top scientists, the authors current an unforeseen imaginative and prescient: the way forward for computing is a synthesis with nature. That imaginative and prescient will swap not just desktop technology but in addition fields as disparate as finance, engineering, and drugs. house engineers are at paintings designing machines that adapt to severe climate and radiation. “Wetware” processing equipped on DNA or bacterial cells races in the direction of fact. One scientist’s “extended analog computer” measures solutions rather than calculating them utilizing ones and zeros. In vigorous, readable prose, Shasha and Lazere take readers on a travel of the way forward for clever machines. 50 illustrations

X-linked mental retardation

This can be a complete and updated survey of psychological retardation because of genes at the X chromosome. medical and laboratory information on one hundred thirty syndromes are awarded in a concise and constant demeanour. every one syndrome is outlined and data is equipped on somatic gains, progress and improvement, neurological indicators, cognitive functionality, imaging and different laboratory findings, and while attainable, the character and localization of the dependable gene.

Coal and Peat Fires: A Global Perspective: Volume 1: Coal - Geology and Combustion

Coal and Peat Fires: a world point of view is a compelling selection of examine performed by means of scientists and engineers around the globe. the 1st of 4 volumes within the assortment, Coal - Geology and Combustion, features chapters that debate the beginning of coal and coal fires; mining and use of coal; combustion and coal petrology; environmental and wellbeing and fitness affects of coal fires; combustion by-products; geochemical, geophysical, and engineering methodologies for learning coal fires; the keep an eye on, extinguishment, and political implications of coal fires; and lots more and plenty extra.

Extra resources for Am I My Genes?: Confronting Fate and Family Secrets in the Age of Genetic Testing

Sample text

It’s easier to make rationalizations, if you don’t have somebody else’s positive tests. Luckily, Sarah lacked the mutation, and has not had any symptoms. For her, the genetic assay provided the information she wanted. People balanced these tensions in the context of medical and economic factors as well. Testing appeared easier in the apparent absence of symptoms. Consequently, a seeming lack of symptoms can encourage testing, but did not always guarantee that a mutation was in fact absent. Simone, the young bookkeeper, felt asymptomatic for HD, but found she had the mutation.

It’s personality. Knowing me, the way I am, I wanted to know, to feel empowered, in control—though obviously there’s not much you can do. But feeling a little more: maybe I can do something about it. This trait contributed to her decision to become a nurse, and was in turn strengthened by her career. She found she had the mutation, and has worked hard to accept it. For HD, too, individuals discussed this notion of a “type” who want to know. Tim, a young lawyer, tested for HD, though asymptomatic.

She continued: When they finally detected it, it was too late. If doctors detect it earlier, they can treat it at the beginning, and extend your life. But by the time they found out, I only had a quarter usage of my lungs. ”: Testing Decisions 35 Especially for rare diseases such as Alpha, physicians may under-test. As the disease is uncommon and its genetic basis relatively new and hence little known, physicians may have little awareness of it. She added, “I still come across doctors who don’t know what it is.

Download PDF sample

Rated 4.72 of 5 – based on 9 votes